In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies HSC localization cues can be defined and manipulated to alter hematopoietic outcomes.
Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell. HSC localization cues can be defined and manipulated to alter hematopoietic outcomes., Publication
Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin HSC localization cues can be defined and manipulated to alter hematopoietic outcomes., Publication
Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning. HSC localization cues can be defined and manipulated to alter hematopoietic outcomes., Publication
Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow HSC localization cues can be defined and manipulated to alter hematopoietic outcomes., Publication
Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor. HSC localization cues can be defined and manipulated to alter hematopoietic outcomes., Publication
CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells. HSC localization cues can be defined and manipulated to alter hematopoietic outcomes., Publication