Proton export alkalinizes intracellular pH and reprograms carbon metabolism to drive normal and malignant cell growth Molecular regulators of HSC quiescence and unique metabolic dependencies of myeloid malignancies.
Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia Molecular regulators of HSC quiescence and unique metabolic dependencies of myeloid malignancies., Publication
Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy Molecular regulators of HSC quiescence and unique metabolic dependencies of myeloid malignancies., Publication
D-cyclins repress apoptosis in hematopoietic cells by controlling death receptor Fas and its ligand FasL Molecular regulators of HSC quiescence and unique metabolic dependencies of myeloid malignancies., Publication
Genome-wide map of nuclear protein degradation shows NCoR1 turnover as a key to mitochondrial gene regulation Molecular regulators of HSC quiescence and unique metabolic dependencies of myeloid malignancies., Publication
Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis. Molecular regulators of HSC quiescence and unique metabolic dependencies of myeloid malignancies., Publication
AKT/FOXO Signaling Enforces Reversible Differentiation Blockade In Myeloid Leukemias. Molecular regulators of HSC quiescence and unique metabolic dependencies of myeloid malignancies., Publication
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a. Molecular regulators of HSC quiescence and unique metabolic dependencies of myeloid malignancies., Publication
Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Molecular regulators of HSC quiescence and unique metabolic dependencies of myeloid malignancies., Publication
Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Molecular regulators of HSC quiescence and unique metabolic dependencies of myeloid malignancies., Publication
